Associate Professor of Neurology University of California Irvine (UCI) Irvine, California, United States
This session will provide an overview of three major cohort studies—All of Us, MIND, and The-HEAD US—that offer rich, diverse datasets for advancing headache research. Dr. Ali Ezzati will discuss each study’s design, target populations, and methods of data collection, with a focus on data integration, patient-reported outcomes, and real-world clinical data. Attendees will learn about the structure and scope of available data, including biospecimens, EHRs, survey instruments, and passive monitoring. The session will also highlight key considerations for accessing and analyzing these resources, offering practical guidance for researchers interested in applying these unique datasets to study migraine, comorbidities, and treatment patterns at scale.
Learning Objectives:
Understand the role of real-world data and digital health platforms in improving the diagnosis, monitoring, and treatment of headache disorders.
Identify challenges and opportunities in implementing precision medicine approaches in the care and study of neurologic diseases using large-scale, real-world datasets.
Describe methodological approaches for designing and implementing real-world studies, including cohort selection, data integration, bias mitigation, and outcome assessment.
